Function to calculate gene signature enrichment scores per spatial position using a rank based approach.
rankEnrich(...)
Arguments
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Arguments passed on to runRankEnrich
gobject Giotto object
sign_matrix Matrix of signature genes for each cell type / process
expression_values expression values to use
reverse_log_scale reverse expression values from log scale
logbase log base to use if reverse_log_scale = TRUE
output_enrichment how to return enrichment output
ties_method how to handle rank ties
p_value calculate p-values (boolean, default = FALSE)
n_times number of permutations to calculate for p_value
rbp_p fractional binarization threshold (default = 0.99)
num_agg number of top genes to aggregate (default = 100)
name to give to spatial enrichment results, default = rank
return_gobject return giotto object
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See also